| 摘要 |
NEW MATERIAL:A compound shown by the formula I [R<1> alkyl, alkenyl, alkynyl, aralkyl, cycloalkyl, alkoxyalkyl, group shown by the formula II (l is 1-3; R<8> is lower alkyl, etc.) or group shown by the formula III (R<9> is lower alkyl); R<2> is lower alkyl; R<3> is alkyl, alkenyl, alkynyl, cycloalkyl, aralkyl, alkoxyalkyl or group shown by the formula IV (m and n are 1-3; R<10> is lower alkyl); R<4> and R<5> are H, nitro, trifluoromethyl, halogen, cyano, etc.; R<6> is group shown by the formula V (R<11> and R<12> are alkyl, alkenyl, etc.), etc.; R<7> is lower alkyl]. EXAMPLE:Methyl 5-bis(methoxy)phosphinyl-1, 2, 6-trimethyl-4-(3-nitrophenyl)- 1,4-dihydropyridine-3-carboxylate. USE:A hypotensor or a vasodilator having high safety. PREPARATION:A compound shown by the formula VI is reacted with a compound shown by the formula VII.
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