发明名称 3-(substituted-ethenyl or ethynyl-thiomethyl) cephems
摘要 The invention relates to new cephem compounds of high antimicrobial activity of the formula: <IMAGE> wherein R1 is amino or a group of the formula: <IMAGE> in which R5 is amino or a protected amino group, R9 is lower alkyl, lower alkenyl, lower alkynyl, cyclo(lower)alkenyl, carboxy(lower)alkyl, protected carboxy(lower)alkyl or saturated 4 to 8-membered heteromonocyclic group containing one sulfur atom, and Z is N or CH, R2 is cyano, phenyl, pyridyl, lower alkylpyridyl, or tri(lower)alkylsilyl, R3 is carboxy or protected carboxy, and A is -CH=CH- or -C 3BOND C-, and pharmaceutically acceptable salt thereof.
申请公布号 US4622318(A) 申请公布日期 1986.11.11
申请号 US19840662604 申请日期 1984.10.19
申请人 FUJISAWA PHARMACEUTICAL CO., LTD. 发明人 TAKAYA, TAKAO;TOZUKA, ZENZABURO;YASUDA, NOBUYOSHI;KAWABATA, KOHJI
分类号 A61K31/545;A61K31/546;A61P31/04;C07D213/32;C07D501/18;C07D501/22;C07D501/24;C07D501/36;(IPC1-7):A61K31/545 主分类号 A61K31/545
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