摘要 |
The invention relates to new cephem compounds of high antimicrobial activity of the formula: <IMAGE> wherein R1 is amino or a group of the formula: <IMAGE> in which R5 is amino or a protected amino group, R9 is lower alkyl, lower alkenyl, lower alkynyl, cyclo(lower)alkenyl, carboxy(lower)alkyl, protected carboxy(lower)alkyl or saturated 4 to 8-membered heteromonocyclic group containing one sulfur atom, and Z is N or CH, R2 is cyano, phenyl, pyridyl, lower alkylpyridyl, or tri(lower)alkylsilyl, R3 is carboxy or protected carboxy, and A is -CH=CH- or -C 3BOND C-, and pharmaceutically acceptable salt thereof.
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