摘要 |
A compound of formula (I): <CHEM> or a pharmaceutically acceptable salt thereof, wherein R<A> is a group of formula (a): <CHEM> wherein T represents a group of formula (b): Q-X<1>-@@-CH2 (b) wherein Q is <CHEM> and where R<1> is a hydrogen or halogen atom or a -CF3, OR<4>, NHR<4>, -NHCOR<4>, -NHCONH2, NHSO2 R<4>, CH2OR<4> or -CH2SO2 R<4> group: R<2> is a hydrogen or halogen atom or an -OR<4> group; R<3> is a hydrogen or halogen atome; and R<4> is hydrogen, C1-6 alkyl or benzyl; X<1> is a bond or -OCH2-; X<2> is a group of formula -CR<5>R<6>-CH2-A- wherein R<5> and R<6> are independently hydrogen or methyl; and A is a bond, -CH2-, or O; T<1> represents a hydrogen atom or a group of formula (b) as defined above in respect of T, such that T<1> and T may be the same or different; R<C> represents a group (a) as defined above in respect of R<A>, such that R<C> and R<A> may be the same or different; provided that when R<A> and R<C> each represent a group of formula: <CHEM> wherein R<2> is oH or -O-benzyl; then when A is a bond, -CH2- or -O, R<1> is not -CH2OH or NHSO2-C1-4 alkyl; processes for the preparation of such compounds and their use in medicine and agriculture. |