| 摘要 |
PURPOSE:The titled preparation for administrating endermically a fixed amount of nicotin, suppressing a demand for smoking accompanied by reduction in nicotin level in the body without pain, obtained by setting a nicotin-containing high polymer substance layer having adhesion at normal temperature on a substate. CONSTITUTION:In a tape preparation obtained by setting a high polymer substance layer having adhesivity at normal temperature on a substrate, nicotin is added to the high polymer substance layer. Especially (meth)acrylate high polymer substance is preferable as the high polymer substance with resect to stability, releasability of nicotin and adhesiveness. Endermic administration of nicotin makes approximately constant nicotin concentration for a long period, suppresses a demand for smoking and makes smoking and reduction in smoking possible without psychological and physiological pains. Handling is much simpler than an existing nicotin administration method. Successively application of preparations having much lower nicotine content can surely show effects.
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