| 摘要 |
TITLE NALBUPHINE-LOCAL ANESTHETIC ANALGESIC COMPOSITION AND METHOD OF PRODUCING ANALGESIA An analgesic composition, particularly in an injectable or opthalmic dosage form, is provided which provides a fast onset of action and an extended duration of action with smaller amounts of the active ingredients. The composition contains nalbuphine or pharmaceutically suitable salt thereof and at least one local anesthetic such as bupivacaine, mepivacaine, and tetracaine. A method of producing analgesia in a mammal is also provided by administering to a mammal intravenously, intraocularly or epidurally nalbuphine or a pharmaceutically suitable salt thereof and at least one local anesthetic. |
