| 摘要 |
The title compds. I [R1=H, lower alkyl, alkynyl, Ph-lower alkyl; R2=H, lower alkoxy; R3=H, lower alkanoyl, etc.!, useful as a heart medicines, were prepd. Thus, a mixt. contg. 3.5 g ethyl2-nitro-5- piperazinyl cinnamate-HCl, 150 ml ethanol, and 45 ml H2O was adjusted to pH 7.0 with NaOH. This mixt. was stirred at 80≦̸C and 5 Kg/cm2 for 4 hrs. with 2 g Raney nickel to give 1.3 g b-(1-piperazinyl)-3,4- dihydrocarbostyril.
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