发明名称 Pharmaceutical compositions with antianginal activity
摘要 The invention relates to pharmaceutical compositions possessing valuable antianginal activity. These compositions show higher activity and more favorable therapeutic indices than the reference compound Prenylamine. Preparation of different kinds of pharmaceutical compositions, such as tablets, dragées, capsules and injectable solutions, containing compounds of general formula (I) <IMAGE> or their acid addition salts as active ingredients, is disclosed, wherein in formula (I) R is phenyl or 4-chlorophenyl; R1 and R2 each represent hydrogen, methyl or isopropyl; R3 and R4 are hydrogen, or together form a chemical bond; n is an integer from 4 to 6; A means trimethylene, if n is 4 or 6; or ethylene, if n is 5.
申请公布号 US4621101(A) 申请公布日期 1986.11.04
申请号 US19850751623 申请日期 1985.07.02
申请人 EGIS GYOGYSZERGYAR 发明人 BUDAI, ZOLTAN;MEZEI, TIBOR;LAY NEE KONYA, ARANKA;PETOCZ, LUJZA;GRASSER, KATALIN;ORR, ZSUZSANNA
分类号 A61K31/15;A61P43/00;C07C251/38;(IPC1-7):A61K31/15 主分类号 A61K31/15
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