KARBAPENEMDERIVATER OG FREMGANGSMAATE TIL FREMSTILLING DERAV.

摘要

Carbapenem derivatives useful as antibacterial agents have the formula (I) wherein: X represents a hydrogen atom or a methyl group; and Y represents a group of the formula: +TR in which: Z represents an oxygen atom or two hydrogen atoms; R1 represents a hydrogen atom, a C1-4 alkyl group, a C1-4 alkanoyl group, or a C1-4 alkanesulfonyl group; R2 represents a hydrogen atom or a hydroxy group, and R3 represents a carbamoyl group; or R2 represents a carbamoyloxy group, and R3 represents a hydrogen atom or a carbamoyl group; R4 represents a hydrogen atom or a C1-4 alkyl group; and represents a 4-6 membered saturated heterocyclic group in which the indicated nitrogen atom is the only hetero-atom; or a pharmaceutically acceptable salt or ester thereof.