发明名称 |
PROCESS FOR PREPARING OPTICALLY UNIFORM BETA-LACTAMS |
摘要 |
There is presented optically uniform beta -lactams of the formulae <IMAGE> wherein Z is a readily cleavable acyl group, R1 is amino or a group convertible into amino, R2 is hydrogen or a readily cleavable protecting group and R3 and R4 each are a lower hydrocarbon group which optionally contains oxygen and which is attached via a carbon atom, whereby these groups can also be joined with one another to form a ring, with the proviso that R1 is a readily cleavable acylamino when R2 is hydrogen, and the corresponding optical antipodes, their manufacture and use in the manufacture of antimicrobially-active beta -lactams as well as novel intermediates usable in their manufacture. |
申请公布号 |
HU190697(B) |
申请公布日期 |
1986.10.28 |
申请号 |
HU19820002715 |
申请日期 |
1982.08.24 |
申请人 |
F.HOFFMANN-LA ROCHE ET CO AG,CH |
发明人 |
HUBSCHWERLEN,CHRISTIAN N,FR;SCHMID,GERARD,CH |
分类号 |
C07D205/08;C07D205/085;C07D277/40;C07D317/28;C07D317/36;C07D317/72;C07D319/12;C07D403/04;C07D405/04;C07D405/14;C07D493/14 |
主分类号 |
C07D205/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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