| 发明名称 |
MERCAPTO ACYL-CARNITINES PROCESS FOR THEIR PREPARATION |
| 摘要 |
Mercapto acyl-carnitines (I) [X-=halogen ion, R=C2-10 mercapto acyl! are prepd. for use as medicines for skin disease and respiratory organ disease. Carnitine hydrochloride is reacted with halogen acyl chloride in inert organic solvent at 30-60≰C to give halogen acyl carnitine. The halogen acyl carnitine is reacted with a compd. selected from alkali metal sulfide and acid sulfide at neutral pH, and held at room temp. to give the title compd..
|
| 申请公布号 |
KR860001903(B1) |
申请公布日期 |
1986.10.24 |
| 申请号 |
KR19820001402 |
申请日期 |
1982.03.31 |
| 申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
TINTI, MARIA ORNELLA;BAGOLINI, CARLO;QUARESIMA, EMMA;WITT, PAOLO DE |
| 分类号 |
C07C323/52;A61K;A61K31/095;A61K31/195;A61K31/205;A61K31/21;A61K31/22;A61K31/23;A61K31/24;A61K31/255;A61K31/265;A61P3/02;A61P11/00;A61P43/00;C07C;C07C67/00;C07C233/45;C07C313/00;C07C319/14;(IPC1-7):C07C149/20;C07C148/00 |
主分类号 |
C07C323/52 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
