| 摘要 |
Substd. azabicycloalkane dicarboxylic acid (I) [A=cyclic ring; n=0,1; R1=C1-4 alkyl containing amino group; R2=C1-4 alkyl, H; q=0,1; R3=alkyl, amino, dicycloalkyl alkyl, phenyl alkyl, -(CH2)p-Y-CH(R4)- R5 (R4=H, lower alkyl; R5=H, lower alkyl, alkoxycarbonyl; Y=S, >N-Q (Q=H, acetyl, benzyl oxycarbonyl); P=1,2)! is prepd. for use as a medicine for hypertension compd. (II) is reacted with alkylester to give cmpd. (III), which is converted into the title compd. (I).
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