发明名称 METHOD FOR THE PREPARATION OF 1,8-DIHYDROXY-10-ACYL-9- ANTHRONES, ESPECIALLY FOR USE IN THE TREATMENT OF PSORIASIS
摘要 <p>The invention relates to a method for the preparation of 1,8-dihydroxy-10-acyl-9-anthrone, especially for use in the treatment of psoriasis, having the formula < IMG > where R is an alkyl group having 2-4 carbon atoms, by using as the initial material 1,8-dihydroxy-9-anthrone and an acid chloride having the formula RCOC1, where R represents the same as above. In accordance with the invention, harmful benzene can be replaced with, for example toluene; this replacing is possible because pyridine is replaced with 2,6-dimethyl pyridine.</p>
申请公布号 CA1212943(A) 申请公布日期 1986.10.21
申请号 CA19840454593 申请日期 1984.05.17
申请人 ORION-YHTYMA OY 发明人 KAIRISALO, PEKKA J.;PIPPURI, AINO K.;HONKANEN, ERKKI J.
分类号 A61K31/12;A61P17/00;B01J31/00;C07B61/00;C07C45/00;C07C45/45;C07C49/747;C07C67/00;(IPC1-7):C07C49/747 主分类号 A61K31/12
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