摘要 |
A new aminoketone derivative having a central muscle relaxant activity which is represented by the following general formula: <CHEM> are the groups defined as I, II or III below, one of R<2> and R<3> is a hydrogen atom and the other is a lower alkyl group; n is 0 when R<1> is I or II, and it is 0 or 1 when R min is III: I: R<1> is a group selected from the groups 1/ &cir& to 7/ &cir& mentioned below and <CHEM> 1/ &cir& a group of the formula <CHEM> (wherein R<4> is a trihalogenomethyl group), 2/ &cir& a group of the formula <CHEM> (wherein R<5> is a fluorine atom, a bromine atom, a lower alkoxyl group, a lower alkyl group, hydroxyl group, CH2=CH-, a phenyl group or <CHEM> 3/ &cir& a group of the formula <CHEM> (wherein R<6> is a halogen atom, a lower alkyl group, <CHEM> CH2=CH- or phenyl group), a |