摘要 |
The topical agents incorporate vitamin E or a vitamin E derivative in an aqueous solution or suspension state. When the topical agents are applied to the skin lesion, the vitamin E or vitamin E derivative penetrates through the epidermis and is easily absorbed by melanocytes in the epidermic basal strutum thereby to remarkably inhibit the melanin generation by interfering the transfer of tyrosinase to premelanosome within the melanocytes. |