Purifying growth hormone-like materials.

摘要

A process is provided for separating impurities from an impure mixture containing growth hormone-like material, which comprises:
(1) applying said mixture to a reverse phase macroporous acryulate ester copolymer resin support at a pH of from about 7 to about 9; and
(2) eluting said growth hormone-like material from said support with an aqueous eluant having a pH of from about 7 to about 9 and containing from about 20% to about 80% by volume of an organic diluent selected from the group consisting of acetone, acetonitrile, and a combination of acetone and acetonitrile.