FREMGANGSMAADE TIL FREMSTILLING AF ANTIBIOTIKUM A/16686 FAKTOR A2 SAMT EVENTUELT YDERLIGERE FAKTOR A1 OG A3 ELLER FYSIOLOGISK ACCEPTABLE SYREADDITIONSSALTE DERAF

摘要

The present invention refers to a chlorine containing antibiotic substance, named antibiotic A/16686 factor A2, in an essentially pure form. The invention also relates to the process for the production of antibiotic A/16686 factors A2 by cultivation of an Actinoplanes strain and to the co-produced antibiotic A/16686 factos A1 and A3. Antibiotic A/16686 factors A1, A2 and A3 as well as the corresponding non-toxic physiologically acceptable acid addition salts are antimicrobial agents particularly active against gram-positive bacteria.