发明名称 DETECTION OF ACTIVATED PLATELETS WITH ANTIBODIES TO CELL SURFACE ANTIGENS
摘要 <p>A diagnostic site-specific imaging reagent in the form of a receptor and an indicating means selectively binds to a specific cell membrance-associated antigen of a blood platelet that is in a stimulated active state but does not substantially bind to a platelet that is in a non-stimulated resting state. In particular, prelabelled monoclonal antibodies and polyclonal antibodies are prepared that bind and image thrombospondin when it is cell membrance-associated on a thrombin-stimulated platelet, thereby providing means for detecting and discriminating between a stimulated active blood platelet and a non-stimulated resting blood platelet.</p>
申请公布号 WO1986005693(A1) 申请公布日期 1986.10.09
申请号 US1986000616 申请日期 1986.03.25
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