发明名称 |
METHOD FOR PREPARING NOVEL 1,1,2,2-TETRAMETHYL-1,2-BIS-(2-FLUOR-4-HYDROXY-PHENYL)-ETHAN DERIVATIVES |
摘要 |
<p>Antitumor compounds corresponding to the following formula: <IMAGE> I in which the substituents R1 and R2 may be the same or different and represent hydrogen, an aminocarbonyl group, a C1-C6 alkylaminocarbonyl group, a di-C1-C6-alkylaminocarbonyl group, the group PO(OH)2, a C2-C8 alkanoyl group, a C2-C8 halogen alkanoyl group or a C3-C8 alkenoyl group, a process for their preparation, and their use in treating oestrogen-receptor-positive-tumors as well as the prostate carcinoma.</p> |
申请公布号 |
GR861480(B) |
申请公布日期 |
1986.10.07 |
申请号 |
GR19860101480 |
申请日期 |
1986.06.06 |
申请人 |
ASTA - WERKE AG CHEMISCHE FABRIK |
发明人 |
DR. SCHONENBERGER HELMUT;DR. HARTMANN W. ROLF;DR. SCHNEIDER MARTIN;SCHWARZ WALTER;DR. ENGEL JURGEN |
分类号 |
C07F9/145;A61K31/055;A61K31/22;A61K31/27;A61K31/66;A61P35/00;C07C39/367;C07C67/00;C07C67/475;C07C69/95;C07C239/00;C07C269/00;C07F9/12;F16J15/00 |
主分类号 |
C07F9/145 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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