发明名称 |
Steroid esters of N-(2-halogenethyl)-N-nitroso-carbamoylamino and acids and peptides therefore, as well as method for preparing them |
摘要 |
Steroid-N-(2-halogen ethyl)-N-nitroso-carbamoylamino acid or peptide esters of the general formula: <IMAGE> +TR <IMAGE> where R1 and R2, which may be identical or different, mean the radical of an amino acid beyond the C atom in the beta position (if present), R3 means the radical of a steroid or a stilbene derivative pharmacologically similar in action, n is a number from 0-5 and Hal stands for chlorine or fluorine, as well as the method for preparing them by the conversion of an appropriate carbamoyl-amino acid or carbamoyl-peptide in a manner known per se with steroid alcohols or the conversion of steroid-amino acid or steroid-peptide esters with corresponding N-nitroso-carbamoylation or corresponding N-nitroso-carbamoyl-amino acids or peptides in a manner known per se.
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申请公布号 |
US4615835(A) |
申请公布日期 |
1986.10.07 |
申请号 |
US19850731861 |
申请日期 |
1985.05.08 |
申请人 |
STIFTUNG DEUTSCHES KREBSFORSCHUNGS ZENTRUM |
发明人 |
EISENBRAND, GERHARD;SCHREIBER, JOACHIM |
分类号 |
C07J41/00;(IPC1-7):C07J1/00 |
主分类号 |
C07J41/00 |
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地址 |
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