摘要 |
<p>Dipeptides of formula (I) and acid addn salts are new. (where R1 = 1-4C alkyl, R2 =H, OH, OCO2R1 or 1-4C alkyl; R3 = H or 1-6C alkyl, R4,R5 = H or 1-6C alkyl, n = 1-6, X=H, OH, OCO2R1, A= cyclohexyl or phenyl opt. substd. with 1 or more 1-6C alkyl, one or more NH2, OH, halogen, NO2 or 1-6C alkoxy, v represents the asymmetric C that may be racemic or have the D or L config. w represents the asymmetric C when R4 and R5 are not the same that may be racemic or have the D or L config.). Several cpds. (I) are claimed e.g. 2,6-dimethyltyrosyl N-(3-phenylpropyl)-D- alancinaminde hydrochloride (Ia) and 2,6-dimethyltyrosyl- N-(3-phenyl-propyl) is ovalinamide monohydrochloride.</p> |