| 摘要 |
<p>Active site cpds. (A) which block immune-complex binding to immunoglobulin Fc receptors and/or immunoglobulin binding to lymphocyte Fc receptors are peptides or their ester, amide, N-acyl or O-cyl derivs. or pharmaceutically acceptable salts. Typical cpds. are of formula (I) or any fragment contg. at least 4 amino acid residues. - A-C-C-D-E-F-G-H-I-J-K-L-M-N (I) - A = Thr, Ser or Ala; B, C and H = Leu, Val, Ile or Ala; D = His; E and F = Gln, Asn, Glu or Asp; G = Trp, Tyr, Phe, Ala, Val, Leu or Ile; I and L = Asp or Glu; J = Gly or Ala; K = Lys, Arg or Orn; M = Tyr; N = Val, Leu, Ile, Ala or Lys.</p> |
