| 发明名称 |
MANUFACTURE OF CARBAPENEM INTEMEDIATE |
| 摘要 |
A process for the preparation of a 4-[3-carboxy-3-diazo-2-oxopropyl]azetidin-2-one of the formula <IMAGE> comprising reacting a 4-acetoxy-2-azetininone of the formula <IMAGE> with a compound of the formula <IMAGE> in an inert solvent, in the presence of a base and of a silylating agent, in a one-pot process. Many of the products are new. The products are useful in the synthesis of carbapenem antibiotics. |
| 申请公布号 |
JPS61215367(A) |
申请公布日期 |
1986.09.25 |
| 申请号 |
JP19860059639 |
申请日期 |
1986.03.19 |
| 申请人 |
BAYER AG |
发明人 |
DEIITAA HEBITSUHI;BORUFUGANGU HARUTOBITSUHI |
| 分类号 |
C07D205/08;C07D205/085;C07D209/48;C07D403/12;C07D409/04;C07D409/06;C07D409/14;C07D411/04;C07D411/14;C07D477/00;C07D477/04;C07D499/06;C07D521/00;C07F7/18;C07F9/40 |
主分类号 |
C07D205/08 |
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