PROCESS FOR PRODUCTION OF ALPHA-HALOALKYLAMIDES

摘要

Amides having the formula RCONR2R3 in which R is alpha -halo-C1-C8-alkyl; R2 is C1-C8 alkyl, and R3 is C1-C8 alkyl, are prepared by reacting an ester with an amine in the presence of a promoter which is a halide of a Group IIIa metal having a molecular weight of 26 or greater, or of a Group IVb metal. The process is particularly suitable for production of a desired optical isomer of such an amide.