| 发明名称 |
IMPROVED METHOD FOR THE ISOLATION AND PURIFICATION OF HEPATITIS B SURFACE ANTIGEN |
| 摘要 |
<p>The supernatant of engineered yeast cells having produced hepatitis B surface antigaen and disrupted in the presence of a polysorbate non-ionic detergent is clarified by addition of urea and adsorbed on colloidal silica from which the purified antigen is desorbed with a low ionic strength buffer supplemented with urea and a polysorbate non-ionic detergent.</p> |
| 申请公布号 |
GR861357(B) |
申请公布日期 |
1986.09.25 |
| 申请号 |
GR19860101357 |
申请日期 |
1986.05.26 |
| 申请人 |
SMITH KLINE - RIT |
发明人 |
VAN WIJNENDAELE FRANS;SIMONET GUY |
| 分类号 |
A61K39/29;C07K14/02 |
主分类号 |
A61K39/29 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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