1,5-BENZOTHIAZEPINDERIVATER SOM ER ANVENDELIGE SOM UTGANGSMATERIALER VED FREMSTILLING AV NYE, TERAPEUTISK AKTIVE 8-KLOR-1,5-BENZOTHIAZEPINDERIVATER, OG FREMGANGSMAATE VED DERES FREMSTILLING.

摘要

Novel 8-chloro-1,5-benzothiazepine derivatives of the formula: (I) wherein R1 is hydrogen, lower alkyl or a group of the formula: R4CO-, each of R2 and R3 is lower alkyl and R4 is hydrogen or lower alkyl, and a pharmaceutically acceptable acid addition salt thereof are disclosed. Said derivative (I) and a pharmaceutically acceptable acid addition salt thereof are useful as hypotensive agents and/or coronary or cerebral vasodilators.