| 摘要 |
NEW MATERIAL:The compound of formula I (R<1> is H or 1-28C hydrocarbon group; R<2>O is 2-4C oxyalkylene; n is 1-4). EXAMPLE:N-hydro-2,12-morpholyl-1,4,7,10-tetraoxacyclododecane. USE:Alkali metal scavenger, metallic ion separator, etc. It can be produced easily in high yield. PREPARATION:The objective compound can be produced by the intramolecular cyclization of the azacrown compound of formula II having dihydroxyl group in the presence of a sulfonic acid chloride (e.g. tosyl chloride) and solid alkali metal hydroxide (preferably powdery sodium hydroxide, etc.) preferably in a solvent such as dioxane at 20-100 deg.C. The amounts of the sulfonic acid chloride and the alkali metal hydroxide are preferably 1mol and 3-5mol per 1mol of the starting compound, respectively. |
