摘要 |
Compounds of the formula:
<CHEM>
[wherein either one of R1 and R2 stands for hydrogen or SO3H and the other one for SO3H, Z stands for &lparstr& CH2 &rparstr& mOR3, &lparstr& CH2 &rparstr& nCOOR4 or
<CHEM>
(wherein m denotes an integer of 1-22, n denotes an integer of 0-21, R3 stands for hydrogen or an acyl group, and R4 for hydrogen or an alkyl group) and pharmacologically acceptable salts thereof may be prepared by
1. reacting a compound of the formula:
<CHEM>
with a sulfating agent, or
2. reacting a compound of the formula:
<CHEM>
[wherein either one of R5 and R6 stands for hydrogen and other for hydroxil] or a salt thereof with a salt of peroxodisulfuric acid in the presence of a base. |