| 发明名称 |
CL-1577-B4 Compound, its production and use. |
| 摘要 |
<p>CL-1577-B, compound is derived by the solvolysis under anhydrous conditions of either CL-1577A compound or CL-1577B compound, obtained from the fermentative action of a purified strain of Actinomycete designated ATCC 39363 under aerobic conditions.</p><p>CL-1577-B<Sub>4</Sub> compound is a potent antimicrobial agent, possessing activity against a number of gram-positive and gram-negative bacteria, yeasts, and fungi. In addition, the compound exhibits in vivo activity against the P388 murine leukemia cell line and in vitro activity against the L1210 murine leukemia cell line.</p><p>A method of making the compound as well as pharmaceutical compositions and methods for their use are also disclosed.</p> |
| 申请公布号 |
EP0194784(A2) |
申请公布日期 |
1986.09.17 |
| 申请号 |
EP19860301435 |
申请日期 |
1986.02.28 |
| 申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
WILTON, JOHN H.;HOKANSON, GERARD C.;FRENCH, JAMES C. |
| 分类号 |
C07G11/00;A61K35/74;A61P31/04;A61P35/00;C12N1/20;C12P1/06;C12R1/01;C12R1/04;(IPC1-7):C07G11/00 |
主分类号 |
C07G11/00 |
| 代理机构 |
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代理人 |
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| 地址 |
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