| 摘要 |
PURPOSE:A percutaneous absorption pharmaceutical for external use, obtained by using a sympathomimetic beta-receptor agent (bronchodilator) and an animal or vegetable oil or organic acid ester or both which are liquid at a specific temperature or below together, and having improved percutaneous absorbability of the above-mentioned drug. CONSTITUTION:A percutaneous absorption pharmaeutical, obtained by incorporating a sympathomimetic beta-receptor agent clinically and widely used as a bronchodilator for bronchial asthma or chronic bronchitis, etc. e.g. isoproterenol or orciprenaline, with an animal or vegetable oil or organic acid ester or both which are liquid at <=37 deg.C in an amount of preferably 1-100pts.wt. based on 1pts.wt. above-mentioned drug at 1:0.05-100 weight ratio between the above- mentioned animal or vegetable oil and/or ester and a base in using the above- mentioned sympathomimetic beta-receptor agent in the administration form of an easily administrable percutaneous absorption pharmaceutical for external use having high remedial effect, and capable of remarkably improving the percutaneous absorption of the above-mentioned drug exhibiting no effect by the well-known absorption promoter, e.g. salicylic acid. |
