发明名称 TRANS-DECALIN DERIVATIVE AND PRODUCTION THEREOF
摘要 NEW MATERIAL:The trans-decalin derivative of formula I (R is alkyl or substituted silyl). EXAMPLE:8-Methoxy-trans-decalin. USE:Useful as a synthetic intermediate for various useful diterpenes. For example, it can be used as a raw material for the synthesis of forskolin having pharmacological activities such as hypotensive activity and 5,5,9- trimethyl-trans-2- decalone, etc., useful as perfumery. PREPARATION:The compound of formula I can be produced by the Diels-Alder reaction of the diene compound of formula II. The reaction is carried out preferably in an inert solvent such as toluene, xylene, etc., at 200-230 deg.C in a sealed tube. A stabilizer such as methylene blue may added to the reaction system.
申请公布号 JPS61204178(A) 申请公布日期 1986.09.10
申请号 JP19850044453 申请日期 1985.03.06
申请人 YAMASA SHOYU CO LTD 发明人 IKEGAMI SHIRO;HASHIMOTO SHUNICHI;SAKATA SHINJI
分类号 C07D307/92;C07C45/00;C07C49/427;C07C49/623;C07C67/00;C07F7/08;C07F7/18;C11B9/00 主分类号 C07D307/92
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