| 摘要 |
NEW MATERIAL:The compound of formula I [R<1> is lower alkyl; R<2> is lower alkyl, lower alkoxycarbonyl-lower alkyl, etc., which have substituent group (OH); R<3> is alkyl, lower hydroxyalkyl, etc.; n is 0, 1 or 2] and its salt. EXAMPLE:8-Hydroxymethyl-5-methoxy-2-benzenesulfenyl-1,4-naphthoquinone. USE:Useful as an anti-inflammatory agent, antirheoumatic agnet, anti-allergic agent, analgesic, diuretic, antithrombotic agent, hypotensor, etc. PREPARATION:The compound of formula I-a can be produced by reacting the compound of formula II [R<2>' is lower alkyl, lower alkoxycarbonyl-lower alkyl, etc., which may have substituent group (OH)] with the thiol compound of formula R3OH in an inert solvent and oxidizing the reaction product with oxygen.
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