| 摘要 |
NEW MATERIAL:The 7,8-epoxidized vitamin D3 derivative of formula I (R is H or OH) and the 5,6-trans isomer of formula II. EXAMPLE:(7R)-19-nor-7,8-epoxy-10-oxovitamin D3. USE:A vitamin D3 derivative having vitamin D-like activity. PREPARATION:The compound of formula I and the 5,6-trans isomer of formula II can be produced, e.g. by oxidizing vitamin D3-7,8-epoxide and its 5, 6-trans isomer with ozone.
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