发明名称 Silicon-bearing amides
摘要 Compounds of the formula I: <IMAGE> (I) wherein each of R1, R2 and R3 is, independently, (a) alkyl having from 1 to 22 carbon atoms; or (b) of the formula <IMAGE> in which m is 0, 1 or 2, and each of R' and R'' is independently a hydrogen atom, alkyl having from 1 to 3 carbon atoms, alkoxy having from 1 to 3 carbon atoms, or halo having an atomic weight of from about 19 to 127; and R is of an aralkyl-, phenyl- tryptophanyl- or benzocycloalkyl-type, are obtained by hydrogenating corresponding alpha - beta ethylenically-unsaturated analogs (II), which in turn are obtained by hydrogenating corresponding alpha - beta acetylenically-unsaturated analogs. Compounds I and II are useful as anti-atheroslerotic agents.
申请公布号 US4611063(A) 申请公布日期 1986.09.09
申请号 US19830526471 申请日期 1983.08.25
申请人 SANDOZ CORP. 发明人 DAMON, II, ROBERT E.
分类号 C07D209/20;C07F3/02;C07F7/08;(IPC1-7):C07F7/10;C07F7/02;C07C103/58;C07D207/30 主分类号 C07D209/20
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