发明名称 |
PROCESS FOR CRYSTALLINE BENZENSULFONATE SALTS OF SULTAMICILLIN |
摘要 |
Cryst. sultamicillin benezenesulfonate salts (I) [X=H or Cl! and their hydrates were prepd. from sultamicillin-HCl and PhSO3H in H2O. A dry blend for oral suspensions was prepd. contg. I(X=H). 2H2O so that when dild. to 100 ml with H2O the suspension contains the equiv. of 50 mg/ml of sultamicillin. (I) have excellent pharmacokinetic properties, optimal soly. and improved stability in bulk and in aq. suspensions.
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申请公布号 |
KR860001279(B1) |
申请公布日期 |
1986.09.05 |
申请号 |
KR19830001708 |
申请日期 |
1983.04.22 |
申请人 |
PFIZER INC. |
发明人 |
BARTH WAYNE ERNEST;JASYS VYTAUTAS JOHN |
分类号 |
C07D519/06;A61K31/43;A61K31/431;A61P31/04;C07D499/00;C07D499/14;C07D499/32;C07D499/64;C07D499/68;C07D499/86;C07D499/87;C07D499/897;C07D519/00;(IPC1-7):C07D499/32 |
主分类号 |
C07D519/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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