| 发明名称 |
Benzoyl urea derivatives having ati-tumor activity. |
| 摘要 |
<p>The present invention relates to a group of new benzoyl urea derivatives of the formula R1-Z-R2 having a better antitumor activity in comparison with known benzoyl urea derivatives. The compounds have been tested in several in vitro test models with different types of tumors.</p> |
| 申请公布号 |
EP0193249(A2) |
申请公布日期 |
1986.09.03 |
| 申请号 |
EP19860200300 |
申请日期 |
1986.02.27 |
| 申请人 |
DUPHAR INTERNATIONAL RESEARCH B.V |
发明人 |
BROUWER, MARIUS S.;VAN HES, ROELOF |
| 分类号 |
A61K31/17;A61K31/33;A61K31/42;A61K31/44;A61K31/4402;A61K31/455;A61K31/495;A61K31/496;A61K31/50;A61K31/505;A61K31/517;A61P35/00;C07C67/00;C07C239/00;C07C275/54;C07C317/44;C07C323/63;C07C325/00;C07C335/26;C07D213/30;C07D213/75;C07D213/81;C07D213/82;C07D213/83;C07D213/89;C07D237/20;C07D237/22;C07D237/24;C07D239/42;C07D239/94;C07D239/95;C07D241/20;C07D241/24;C07D261/14;C07D275/02;C07D275/03;C07D277/48;C07D277/60;C07D277/82;C07D283/00;C07D285/00;C07D285/06;C07D285/08;C07D285/12;C07D285/135;C07D333/24;C07D295/14;C07D307/68;C07D307/87;C07D333/38;C07D521/00;(IPC1-7):C07C127/22 |
主分类号 |
A61K31/17 |
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