摘要 |
PURPOSE:To provide a pulverized REISHI (Coriolus versicolor) containing a large amount of ganoderic acid. CONSTITUTION:REISHI [fungus belonging to Polyporaceae family, e.g. SEKISHI, KOKUSHI, HAKUSHI, OUSHI, SHISHI, etc. (all are kinds of REISHI classified by colors) is dried, cut in the form of mince, frozen at -10--80 deg.C, and crushed with a crusher such as ball mill in frozen state. The crushed product is taken out of the mill, returned to normal temperature, and sieved to obtain the powder of 10-200 mesh. The fraction left on a 10-mesh sieve is frozen again and crushed with a ball mill. The fraction of 10-200 mesh is sterilized at a low temperature (<=60 deg.C) to obtain the crushed REISHI containing a large amount of ganoderic acid of formula as an active component. The compound of formula effectively inhibits the activity of cyclooxynase which is an arachidonic acid metabolism enzyme. EFFECT:The sensible threshold of bitter taste with the tongue can be lowered, and the dose can be decreased. |