发明名称 N-(1-(4-AMINO-6,7-DIALKOXY-2-QUINAZOLINYL)-4-PIPERIDYL)-OXAZOLIDINE-2,4-DIONES
摘要 Compounds of the formula <IMAGE> wherein R1 and R2, which may be identical to or different from each other, are each independently hydrogen, straight or branched alkyl of 1 to 8 carbon atoms or arylmethyl; or R1 and R2, together with each other, are -(CH2)4 or -(CH2)5-; and R3 and R4, which may be identical to or different from each other, are each independently hydrogen, straight or branched alkyl of 1 to 4 carbon atoms or arylmethyl; or R3 and R4, together with each other, are -CH3- or -CH2-CH2-; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful for the treatment of cardiovascular diseases, especially hypertension.
申请公布号 PH20015(A) 申请公布日期 1986.08.28
申请号 PH19640000295 申请日期 1983.09.20
申请人 BOEHRINGER INGELHEIM KG. 发明人 ANTON MENTRUP;ERNST-OTTO RENTH;KURT SCHROMM;WOLFRAM GAIDA;WOLFGANG HOEFKE
分类号 C07D239/95;A61K31/505;A61K31/517;A61P9/08;A61P9/12;A61P25/02;C07D263/44;C07D401/14;C07D413/04;C07D413/14;C07D491/056 主分类号 C07D239/95
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