| 摘要 |
<p>The present invention is dealing with disaccharide or trisaccharide derivatives of the lipid A type, having the formula 1
<Chemistry id="chema01" num="0001"><Image id="ia01" he="30" wi="83" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein
<UnorderedLists id="ula01" listStyle="none"><ListItem>R<Sub>1</Sub> = OH, the group -O(CH<Sub>2)n</Sub>-CH<Sub>3</Sub> or a β-1,6-bonded glucosamine derivative having the formula il
<Chemistry id="chema02" num="0002"><Image id="ia02" he="39" wi="84" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry><Chemistry id="chema03" num="0003"><Image id="ia03" he="28" wi="64" file="IMGA0003.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry><Chemistry id="chema04" num="0004"><Image id="ia04" he="23" wi="85" file="IMGA0004.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry><Chemistry id="chema05" num="0005"><Image id="ia05" he="22" wi="85" file="IMGA0005.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry></ListItem><ListItem>m, q, s and v each independently is 6-14</ListItem><ListItem>n, p, rand t each independently is 0-16, and</ListItem><ListItem>X represents two hydrogen atoms or - when R<Sub>2</Sub> = H - also oxygen, which have interesting immuno-modulating, more particularly immuno-stimulating properties.</ListItem></UnorderedLists></p> |
