PROLONGED-ACTION IMMUNOTOXINS CONTAINING A GLYCOPEPTIDE CONSTITUENT WHICH INACTIVATES RIBOSOMES,MODIFIED ON ITS POLYSACCHARIDE UNITS

摘要

Prolonged-acting immunotoxin consisting of a conjugate in which an antibody or antibody fragment is coupled, via a covalent structure containing a disulphide group or a thioether group, to a ribosome-inactivating glycoprotein having a prolonged action obtained by oxidation of its saccharide moieties with periodate ions.