发明名称 Pharmaceutical agent for the treatment of diabetes mellitus
摘要 The invention relates to medicaments consisting of a physiologically acceptable excipient and an active compound combination of (a) an insulin derivative of the formula I <IMAGE> (I) in which R1 denotes H or H-Phe, R30 represents the radical of a neutral L-aminoacid and R31 represents a physiologically acceptable organic group of basic character with up to 50 carbon atoms, with an isoelectric point between 5.8 and 8.5, and (b) an insulin of the formula I in which R1 denotes H or H-Phe, R30 represents Ala, Thr or Ser and R31 denotes OH, and to its use for the treatment of diabetes mellitus.
申请公布号 US4608364(A) 申请公布日期 1986.08.26
申请号 US19840632859 申请日期 1984.07.20
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 GRAU, ULRICH
分类号 A61K38/00;A61K38/28;C07K14/62;C07K14/625;(IPC1-7):A61K37/26 主分类号 A61K38/00
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