摘要 |
Compounds of the formula <IMAGE> where X is selected from hydrogen, C1 to C22 alkyl or alkenyl, or an electron withdrawing group; n=0 or 1 and m=0, 1, 2 or 3; but n and m are not O simultaneously; R1 and R2 independently are hydrogen, C1 to C6 alkyl, an electron withdrawing group, or R4; R3 is H, C1 to C6 alkyl or cycloalkyl, or R4; and R4 independently at each occurrence, has the formula <IMAGE> where Y is hydrogen or an electron withdrawing group; and wherein M is a pharmaceutically acceptable cation, are potent inhibitors of lipoxygenase enzymes.
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