发明名称 Lipoxygenase inhibiting compounds
摘要 Compounds of the formula <IMAGE> where X is selected from hydrogen, C1 to C22 alkyl or alkenyl, or an electron withdrawing group; n=0 or 1 and m=0, 1, 2 or 3; but n and m are not O simultaneously; R1 and R2 independently are hydrogen, C1 to C6 alkyl, an electron withdrawing group, or R4; R3 is H, C1 to C6 alkyl or cycloalkyl, or R4; and R4 independently at each occurrence, has the formula <IMAGE> where Y is hydrogen or an electron withdrawing group; and wherein M is a pharmaceutically acceptable cation, are potent inhibitors of lipoxygenase enzymes.
申请公布号 US4608390(A) 申请公布日期 1986.08.26
申请号 US19850727465 申请日期 1985.04.26
申请人 ABBOTT LABORATORIES 发明人 SUMMERS, JR., JAMES B.
分类号 C12N9/99;A61K31/13;A61K31/165;A61K31/195;A61K31/215;A61P11/00;A61P17/00;A61P29/00;A61P37/08;A61P43/00;C07C67/00;C07C239/00;C07C259/06;(IPC1-7):C07C83/10;A61K31/185;A61K31/04 主分类号 C12N9/99
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