发明名称 Use of cyclopentadienyl metal-acido complexes for the treatment of cancer and pharmaceutical compositions containing said complexes
摘要 This disclosure relates to the use of cytostatically active cyclopentadienyl metal-acido complexes for the treatment of transplanted tumor and pharmaceutical compositions containing said complexes. The organometallic compounds employed in the invention have the general formula: <IMAGE> wherein M is Ti, Zr, Hf, V, Nb, Ta, Mo or W, Cp and Cp' are, e.g., cyclopentadienyl or substituted cyclopentadienyl radicals, Z is an optional straight-chain or branched bridging group having 1 to 3 C, Si or Ge atoms in the bridging chain and X and X' are, e.g., halogen, cyanate, isocyanate, thiocyanate, isothiocyanate, azide or phenylacetylide.
申请公布号 US4608387(A) 申请公布日期 1986.08.26
申请号 US19830538539 申请日期 1983.10.03
申请人 KOEPF, HARTMUT;KOEPF-MAIER, PETRA 发明人 KOEPF, HARTMUT;KOEPF-MAIER, PETRA
分类号 A61K31/28;A61K31/695;A61P35/00;(IPC1-7):A61K31/28 主分类号 A61K31/28
代理机构 代理人
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