发明名称 NOVEL PIPERAZINECARBOXAMIDES HAVING A PHENOXYALKYL OR THIOPHENOXYALKYL SIDE CHAIN
摘要 Novel compounds of formula (I), wherein R1 is selected from hydrogen, halogen; or trifluoromethyl; X is oxygen or sulfur; R2 and R3 are the same or different and selected from hydrogen or lower alkyl; m is 2 or 3; Y is oxygen or sulfur; Z is selected from : -NR4R5, formulae (II), (III) or (IV), wherein R4 and R5 are the same or different and selected from hydrogen, alkyl, cycloalkyl, cycloalkyl-alkyl, hydroxy-alkyl, alkoxyalkyl or alkanoyloxyalkyl, phenyl or phenyl-alkyl, wherein the phenyl groups may be unsubstituted or monosubstituted with halogen or CF3; n is 0, 1, 2 or 3; R6 and R7 are the same or different and selected from hydrogen, lower alkyl, hydroxy, lower alkoxy or lower alkanoyloxy; p is 2 or 3; R8 and R9 are the same or different and selected from hydrogen or lower alkyl; R10 is hydrogen, lower alkyl or lower alkanoyl. The new compounds can be used for treating mental disorders.
申请公布号 WO8604584(A1) 申请公布日期 1986.08.14
申请号 WO1986SE00038 申请日期 1986.01.31
申请人 AKTIEBOLAGET LEO 发明人 FEX, TOMAS;OLSSON, KNUT, GUNNAR;ABRAMO, AINA, LISBETH;CHRISTENSSON, ERIK, GUNNAR
分类号 C07D295/20;A61K31/455;A61K31/495;A61K31/535;A61K31/5375;A61K31/55;A61P25/02;A61P25/20;A61P25/24;A61P25/26;C07D211/46;C07D241/24;C07D243/08;C07D295/215;C07D411/00;C07D411/06;C07D413/00;C07D413/06;(IPC1-7):C07D295/14;C07D401/06;C07D241/04 主分类号 C07D295/20
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