| 摘要 |
A 987P fimbriae-producing microorganism shows 987P fimbriae in an amount corresponding to five percent or more by weight of its protein content. For exemple, 10 percent by weight of purified 987P fimbriae can be extracted from E. coli NCTC 11,665 calculated from the total protein content of the cells. The microorganism is used in the form of whole cells and/or cell wall material for production of a vaccine for the immunization of pigs, for example, sows or sucking pigs, against pathogenic E. coli strains. The vaccine is produced by culturing of the 987P fimbriae-producing microorganism. If desired, the microorganism is then killed, and the cell wall material comprising 987P fimbriae is isolated whereupon it is mixed with a carrier substance and/or an adjuvant. |
