| 摘要 |
PURPOSE:To obtain the titled compound by a simple operation efficiently in high quality in high yield, by reacting a resorcin compound and a lower carboxylic acid halide as raw materials in the presence of a zinc halide and an inert solvent in a heterogeneous state. CONSTITUTION:A resorcin compound shown by the formula (R1-R3 are H, or <=5C alkyl) such as resorcin, etc., is reacted with <=5C monocarboxylic acid halide such as acetic acid chloride, etc., in an inert solvent such as nitrobenzene, etc., in the presence of a zinc halide such as zinc chloride, etc., at -10-100 deg.C for 0.1-5hr, the reaction mixture is subjected to solid-liquid separation, and the prepared solid substance is washed with water, to give the aimed high- quality compound such as 2,4-dihyroxyacetophenone, etc. EFFECT:Complicated operations such as distillation, recrystallization, etc., after the reaction are not required, and separating operation can be simplified. USE:An intermediate for fine chemicals, and a raw material for drugs, agricultural chemicals, photosensitive materials, perfume, resins, etc.
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