Retro-inverso analogs of the bradykinin potentiating peptide bpp 5a.

摘要

New partially retro-inverso peptides of the following general formula <CHEM> wherein R<1> and R<2> are the same or different and represent, each independently, the side chain of the aminoacid residues present in the naturally occuring peptides, X is -S-Ph or -O-CH2-Ph and Z is a hydroxy, alkoxy or amino group, are described as well as a suitable method for their preparation. The new compounds are useful as antihypertensive agents.