Radio labeled dihematoporphyrin ether and its use in detecting and treating neoplastic tissue.

摘要

Radiolabeled dihematopophyrin ether having the following general formula
<Chemistry id="chema01" num="0001"><Image id="ia01" he="63" wi="149" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein at least one of R<Sub>1</Sub>-R<Sub>6</Sub> is a moiety labeled with a radionuclide imaging agent is useful in providing a non--invasive nuclear scintillation image. This dihematoporphyrin ether localizes in neoplastic tissue and thus provides a method of imaging and recording the location of neoplastic tissue. When the labeling agent has an adequate component of particulate radiation, the dihematoporphyrin ether can be used as a therapeutic agent as well as a diagnostic imaging agent