发明名称
摘要 PURPOSE:Finely-ground polyvalent metal salt of 2-mercaptopyridin-N-oxide useful as an antimicrobial composition, having improved dispersion stability, and improved adsorbability to the skin and hair, obtained by pulverizing particle diameters of the substance into <= a specific particle diameter distribution. CONSTITUTION:A polyvalent metal salt of 2-mercaptopyridin-N-oxide is stirred with a rigid medium such as Ottawa sand, glass, alumina, zircon having <=0.5mm. particle diameter to give finely-ground polyvalent metal salt of 2-mercaptopyridin-N-oxide comprising >=50wt% particles having <=0.2mu particle diameter. The polyvalent metal salt of 2-mercaptopyridin-N-oxide has preferable form of dispersion. EFFECT:Providing shampoo, hair rinse, etc. with improved antimicrobial action and suppressing action on dandruff. Composition can be prepared efficiently and in a short time.
申请公布号 JPS6135186(B2) 申请公布日期 1986.08.12
申请号 JP19830122845 申请日期 1983.07.06
申请人 KAO CORP 发明人 IMAMURA TAKASHI;NOZAKI TOSHIO;NISHINO KENJI;KANAI HIROYUKI
分类号 A61K8/00;A61K8/49;A61K8/58;A61K31/44;A61K31/555;A61P17/00;A61P31/04;A61Q5/00;A61Q5/02;A61Q5/12;C07D213/89;C07F3/06 主分类号 A61K8/00
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