Preparation of 1,1-diphenyl-2-carboethoxycyclopropane

摘要

An improved process is disclosed for preparing racemic 1,1-diphenyl-2-carboethoxycyclopropane from 1,1-diphenylethylene and ethyl diazoacetate as reactants. It involves conducting the reaction in the absence of a metallic-based catalyst and at a reaction temperature sufficiently in excess of 60 DEG C. to permit a yield of at least 20 percent to be obtained. Preferred conditions are given for obtaining yields in excess of 80 percent. Related processes are also disclosed based on certain substituted 1,1-diphenylethylenes with at least one substituent in at least one phenyl group.