ANTI IMMUNE COMPLEX ANTIBODY AND PREPARATION THEREOF

摘要

A novel antibody is obtained by using an antigen, a complex of an antigen and a F(ab min )2 fragment of the human antibody of this antigen or an aggregate of F(ab min 2) fragment of human immunoglobulin. This antibody reacts with an immune complex in serum of a patient subject to systemic lupus erythematosus and with an immune complex in serum of a patient subject to rheumatoid arthritis, but does not react with an aggregated IgG. The amount of immune complex in a blood serum is easily and exactly determined by using this antibody.